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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHB3
All Species:
21.52
Human Site:
Y593
Identified Species:
59.17
UniProt:
P54753
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54753
NP_004434.2
998
110330
Y593
R
H
G
S
D
S
E
Y
T
E
K
L
Q
Q
Y
Chimpanzee
Pan troglodytes
P0C0K6
1020
110674
E629
R
R
G
T
G
Y
T
E
Q
L
Q
Q
Y
S
S
Rhesus Macaque
Macaca mulatta
XP_001097522
1001
110812
Y596
R
H
G
S
D
S
E
Y
T
E
K
L
Q
Q
Y
Dog
Lupus familis
XP_545232
1132
124546
Y727
R
H
G
S
D
S
E
Y
T
E
K
L
Q
Q
Y
Cat
Felis silvestris
Mouse
Mus musculus
P54754
993
109567
Y588
R
H
G
P
D
A
E
Y
T
E
K
L
Q
Q
Y
Rat
Rattus norvegicus
P09759
984
109865
L579
E
A
V
Y
S
D
K
L
Q
H
Y
S
T
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q07498
988
109560
Y583
R
N
S
T
D
P
E
Y
T
E
K
L
Q
Q
Y
Frog
Xenopus laevis
Q91735
974
108246
Y569
R
N
D
S
E
S
E
Y
T
E
K
L
Q
Q
Y
Zebra Danio
Brachydanio rerio
O13146
981
109636
M586
Q
D
P
E
E
E
K
M
Q
F
Q
H
G
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.3
97.6
85.6
N.A.
95.9
70.2
N.A.
N.A.
83.3
77.4
54.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
63.5
98.3
86.2
N.A.
96.7
81.6
N.A.
N.A.
90.6
87.5
69
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
86.6
0
N.A.
N.A.
73.3
80
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
93.3
6.6
N.A.
N.A.
86.6
93.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
12
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
12
0
56
12
0
0
0
0
0
0
0
0
0
% D
% Glu:
12
0
0
12
23
12
67
12
0
67
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% F
% Gly:
0
0
56
0
12
0
0
0
0
0
0
0
12
12
0
% G
% His:
0
45
0
0
0
0
0
0
0
12
0
12
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
23
0
0
0
67
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
12
0
12
0
67
0
0
0
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
12
0
12
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
0
0
0
0
0
0
0
34
0
23
12
67
67
0
% Q
% Arg:
78
12
0
0
0
0
0
0
0
0
0
0
0
12
12
% R
% Ser:
0
0
12
45
12
45
0
0
0
0
0
12
0
12
12
% S
% Thr:
0
0
0
23
0
0
12
0
67
0
0
0
12
0
0
% T
% Val:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
12
0
67
0
0
12
0
12
0
67
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _